Michael Briggs Selected Research

1- (4- (3- chlorophenylamino)- 1- methyl- 1H- pyrrolo(3,2- c)pyridin- 7- yl)- 1- morpholin- 4- ylmethanone

10/2009

Discovery of 1-[4-(3-chlorophenylamino)-1-methyl-1H-pyrrolo[3,2-c]pyridin-7-yl]-1-morpholin-4-ylmethanone (GSK554418A), a brain penetrant 5-azaindole CB2 agonist for the treatment of chronic pain.

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Michael Briggs Research Topics

Disease

1	Pneumonia (Pneumonitis) 01/2022
1	Ochronosis 01/2020
1	Disease Progression 01/2020
1	Alkaptonuria 01/2020
1	Bacterial Conjunctivitis 01/2017
1	Conjunctivitis 01/2017
1	Neoplasms (Cancer) 09/2015
1	Glioblastoma (Glioblastoma Multiforme) 09/2015
1	Migraine Disorders (Migraine) 02/2010
1	Acute Pain 10/2009
1	Chronic Pain 10/2009
1	Weight Loss (Weight Reduction) 03/2007
1	Necrosis 01/2007
1	Insulin Resistance 01/2007

Drug/Important Bio-Agent (IBA)

1	EndotoxinsIBA 01/2022
1	nitisinone (Orfadin)FDA Link 01/2020
1	Homogentisic AcidIBA 01/2020
1	Chloramphenicol (Chloromycetin)FDA Link 01/2017
1	Methicillin (Metin)FDA Link 01/2017
1	Ciprofloxacin (Cipro)FDA LinkGeneric 01/2017
1	Gentamicins (Gentamicin)FDA LinkGeneric 01/2017
1	Erlotinib Hydrochloride (CP 358,774)FDA Link 09/2015
1	Adenosine Monophosphate (AMP)IBA 09/2015
1	Biomarkers (Surrogate Marker)IBA 09/2015
1	Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA 09/2015
1	OxadiazolesIBA 02/2010
1	Calcitonin Gene-Related Peptide Receptor AntagonistsIBA 02/2010
1	5-azaindoleIBA 10/2009
1	1- (4- (3- chlorophenylamino)- 1- methyl- 1H- pyrrolo(3,2- c)pyridin- 7- yl)- 1- morpholin- 4- ylmethanoneIBA 10/2009
1	6-azaindoleIBA 10/2009
1	Triiodothyronine (Liothyronine)FDA LinkGeneric 03/2007
1	Thyroxine (Levothyroxine)FDA LinkGeneric 03/2007
1	Zidovudine (Retrovir)FDA LinkGeneric 01/2007
1	CytokinesIBA 01/2007
1	Lopinavir FDA Link 01/2007
1	Stavudine (Zerit)FDA LinkGeneric 01/2007
1	ChemokinesIBA 01/2007
1	Nelfinavir (Viracept)FDA Link 01/2007
1	Interleukin-1beta (Interleukin 1 beta)IBA 01/2007
1	AdipokinesIBA 01/2007

Therapy/Procedure

1	Therapeutics 09/2015